The De La Salle-College of Saint Benilde Blazers and Lady Blazers are the NCAA senior varsity teams of De La Salle–College of Saint Benilde.
The Blazers were formerly a member of the National Capital Region Athletic Association (NCRAA) before being admitted to the NCAA in 1998. They then went on to win their first NCAA seniors basketball title in 2000, the fastest for an expansion squad.
The college's male juniors team are referred to as the Benilde–LSGH Junior Blazers (officially the Benilde–LSGH Greenies) of La Salle Green Hills.
Almost all sports programs of the Blazers excel in their events, leading to the De La Salle-College of Saint Benilde winning its first ever General Championship in NCAA Season 81, and again in NCAA Season 83, NCAA Season 84, NCAA Season 89, and NCAA Season 90.